A comprehensive, open-access resource providing the research community with information, tools and phenotyping algorithms for UK electronic health records data.
Rule-based phenotyping algorithms using four national structured UK EHR data sources: primary care (CPRD), hospitalizations (HES) and mortality (ONS). Phenoypes have been extensively validated by generating six layers of evidence: aetiological, prognostic, case-note review, genetic, cross-EHR and cross-country replication.
CALIBER EHR phenotyping algorithms have been used in >60 peer-reviewed journal publications by 140 investigators from >40 national and international research groups.
Access codelists created and curated using UK primary care, hospital care and mortality EHR data sources using using Read codes (a subset of SNOMED-CT), ICD-9, ICD-10, OPCS-4 (analogous to Current Procedural Terminology terms) and Gemscript.