Phenotype
Type
Data sources
Clinical Terminologies
Valid event date range
Sex
Agreed
AuthorsPrimary Care (incident)
In the Clinical Practice Research Datalink (CPRD, primary care data) we ascertained hypertension (HT) cases by searching for Read terms related to HT diagnosis OR inference from blood pressure reading OR prescriptions of blood pressure lowering medications.
Blood pressure readings: presence of at least 3 systolic or diastolic high blood pressure readings within a 1 year period (SYS_BP >= 150 mmHg OR DIAS_BP >= 90 mmHg), or at least 2 systolic or diastolic high blood pressure readings within a 6 month period. For diabetic patients and patients over 60 years old, a lower threshold is used (SYS_BP >= 140 mmHg OR DIAS_BP >= 90 mmHg).
Medication: at least two prescriptions of blood pressure lowering medication within 6 months from British National Formulary chapters 2.2.1 (Thiazides), 2.2.3 (loop diuretics), 2.2.4 (Potassium-sparing diuretics with other diuretics), 2.4 (beta blockers), 2.5 (hypertension and heart failure related medication) and 2.6.2 (calcium-channel blockers).
| Read code | Read term | CALIBER category |
|---|---|---|
| 6624.00 | Borderline hyperten:yearly obs | Hypertension |
| 6627.00 | Good hypertension control | Hypertension |
| 6628.00 | Poor hypertension control | Hypertension |
| 662F.00 | Hypertension treatm. started | Hypertension |
| 662G.00 | Hypertensive treatm.changed | Hypertension |
| 662O.00 | On treatment for hypertension | Hypertension |
| 662b.00 | Moderate hypertension control | Hypertension |
| 662c.00 | Hypertension six month review | Hypertension |
| 662d.00 | Hypertension annual review | Hypertension |
| 662r.00 | Trial withdrawal of antihypertensive therapy | Hypertension |
| 7Q01.00 | High cost hypertension drugs | Hypertension |
| 8B26.00 | Antihypertensive therapy | Hypertension |
| 8BL0.00 | Patient on maximal tolerated antihypertensive therapy | Hypertension |
| 8I3N.00 | Hypertension treatment refused | Hypertension |
| F404200 | Blind hypertensive eye | Hypertension |
| F421300 | Hypertensive retinopathy | Hypertension |
| G2...00 | Hypertensive disease | Hypertension |
| G2...11 | BP - hypertensive disease | Hypertension |
| G20..00 | Essential hypertension | Hypertension |
| G200.00 | Malignant essential hypertension | Hypertension |
| G201.00 | Benign essential hypertension | Hypertension |
| G202.00 | Systolic hypertension | Hypertension |
| G203.00 | Diastolic hypertension | Hypertension |
| G20z.00 | Essential hypertension NOS | Hypertension |
| G20z.11 | Hypertension NOS | Hypertension |
| G21..00 | Hypertensive heart disease | Hypertension |
| G210.00 | Malignant hypertensive heart disease | Hypertension |
| G210000 | Malignant hypertensive heart disease without CCF | Hypertension |
| G210100 | Malignant hypertensive heart disease with CCF | Hypertension |
| G211.00 | Benign hypertensive heart disease | Hypertension |
| G211000 | Benign hypertensive heart disease without CCF | Hypertension |
| G211100 | Benign hypertensive heart disease with CCF | Hypertension |
| G21z.00 | Hypertensive heart disease NOS | Hypertension |
| G21z000 | Hypertensive heart disease NOS without CCF | Hypertension |
| G21z011 | Cardiomegaly - hypertensive | Hypertension |
| G21z100 | Hypertensive heart disease NOS with CCF | Hypertension |
| G21zz00 | Hypertensive heart disease NOS | Hypertension |
| G22..00 | Hypertensive renal disease | Hypertension |
| G220.00 | Malignant hypertensive renal disease | Hypertension |
| G221.00 | Benign hypertensive renal disease | Hypertension |
| G222.00 | Hypertensive renal disease with renal failure | Hypertension |
| G22z.00 | Hypertensive renal disease NOS | Hypertension |
| G22z.11 | Renal hypertension | Hypertension |
| G23..00 | Hypertensive heart and renal disease | Hypertension |
| G230.00 | Malignant hypertensive heart and renal disease | Hypertension |
| G231.00 | Benign hypertensive heart and renal disease | Hypertension |
| G232.00 | Hypertensive heart&renal dis wth (congestive) heart failure | Hypertension |
| G233.00 | Hypertensive heart and renal disease with renal failure | Hypertension |
| G234.00 | Hyperten heart&renal dis+both(congestv)heart and renal fail | Hypertension |
| G23z.00 | Hypertensive heart and renal disease NOS | Hypertension |
| G2y..00 | Other specified hypertensive disease | Hypertension |
| G2z..00 | Hypertensive disease NOS | Hypertension |
| G672.00 | Hypertensive encephalopathy | Hypertension |
| G672.11 | Hypertensive crisis | Hypertension |
| Gyu2.00 | [X]Hypertensive diseases | Hypertension |
| L122.00 | Other pre-existing hypertension in preg/childbirth/puerp | Hypertension |
| L122000 | Other pre-existing hypertension in preg/childb/puerp unspec | Hypertension |
| L122100 | Other pre-existing hypertension in preg/childb/puerp - deliv | Hypertension |
| L122300 | Other pre-exist hypertension in preg/childb/puerp-not deliv | Hypertension |
| L122z00 | Other pre-existing hypertension in preg/childb/puerp NOS | Hypertension |
| L127.00 | Pre-eclampsia or eclampsia with pre-existing hypertension | Hypertension |
| L127z00 | Pre-eclampsia or eclampsia + pre-existing hypertension NOS | Hypertension |
| L128.00 | Pre-exist hypertension compl preg childbirth and puerperium | Hypertension |
| L128000 | Pre-exist hyperten heart dis compl preg childbth+puerperium | Hypertension |
| L128200 | Pre-exist 2ndry hypertens comp preg childbth and puerperium | Hypertension |
| TJC7.00 | Adverse reaction to other antihypertensives | Hypertension |
| TJC7z00 | Adverse reaction to antihypertensives NOS | Hypertension |
| U60C500 | [X]Oth antihyperten drug caus advers eff in therap use, NEC | Hypertension |
| U60C511 | [X] Adverse reaction to other antihypertensives | Hypertension |
| U60C51A | [X] Adverse reaction to antihypertensives NOS | Hypertension |
| 6146200 | Hypertension induced by oral contraceptive pill | Secondary hypertension |
| G24..00 | Secondary hypertension | Secondary hypertension |
| G240.00 | Secondary malignant hypertension | Secondary hypertension |
| G240000 | Secondary malignant renovascular hypertension | Secondary hypertension |
| G240z00 | Secondary malignant hypertension NOS | Secondary hypertension |
| G241.00 | Secondary benign hypertension | Secondary hypertension |
| G241000 | Secondary benign renovascular hypertension | Secondary hypertension |
| G241z00 | Secondary benign hypertension NOS | Secondary hypertension |
| G244.00 | Hypertension secondary to endocrine disorders | Secondary hypertension |
| G24z.00 | Secondary hypertension NOS | Secondary hypertension |
| G24z000 | Secondary renovascular hypertension NOS | Secondary hypertension |
| G24z100 | Hypertension secondary to drug | Secondary hypertension |
| G24zz00 | Secondary hypertension NOS | Secondary hypertension |
| Gyu2100 | [X]Hypertension secondary to other renal disorders | Secondary hypertension |